euVENTION Summer School: innovations for people with chronic diseases

euVENTION Summer School: innovations for people with chronic diseases

From July 21 – August 2 in Heidelberg, Germany, we present euVENTION, the Summer School for Innovation in Chronic Disease Intervention. After a successful edition last year in Leiden, this EIT Health Summer School is organized by Heidelberg University with Leyden Academy on Vitality and Ageing and Universidade de Coimbra (Portugal). During the two-week programme, multidisciplinary teams of students will develop ideas into business models that can address challenges provided by industry partners, academia, and non-profit organisations. The innovations they work on should contribute to healthy living and active aging for people with chronic diseases.

Innovation to address chronic diseases
Participants in the euVENTION Summer School are challenged to come up with healthcare solutions using co-creation, design thinking, rapid prototyping and business modelling. Participants are prepared for this activity with inspirational lectures about the basics of innovation to address chronic diseases. This is followed by guided working groups to help students develop their innovation skills. Participants co-design, validate and test ideas at each stage, with all target audiences concerned. By the end of euVENTION, participants will have gone through all phases of a real-world innovation trajectory, and they will have acquired the necessary set of skills and knowledge to start entrepreneurial activities.

Open-minded people invited to apply
euVENTION welcomes applications from all open-minded people who want to change the future of health. The Summer School is designed for PhD students, but all dedicated master students, young professionals or motivated individuals are welcome to apply, as we believe multi-disciplinary teams can come up with the best and most innovative solutions.

Please visit the euVENTION website for more information, the full programme and the registration form. For an overview of Summer Schools in 2019, visit the EIT Health website.

8.5 million euros for healthy ageing and vitality research

8.5 million euros for healthy ageing and vitality research

Leiden, The Netherlands, 24 April 2019 – A wide-ranging and multi-disciplinary Dutch team of experts of research into ageing has obtained a grant in excess of 8.5 million euros for a comprehensive research programme of both factors and practical solutions which can contribute to ageing healthily as well as improving personal vitality. The ambition of the team is to identify early signs of functional decline in seniors, attenuate decline and restore body functions to allow seniors to increase the number of healthy years. In this research programme, which starts in October 2019, nine institutions and eight private partners participate, including Leyden Academy on Vitality and Ageing.

The Principal Investigator of the programme is Prof. dr. Eline Slagboom, chair of the Dutch Society of Research on Ageing (DuSRA) and researcher at the Leiden University Medical Center (LUMC). “The life expectancy of Dutch citizens is still increasing. However together with greying of the population, the number of seniors with one or more age-related disease conditions is also increasing. Consequently, we want to generate a platform for enduring relationships between researchers and citizens to achieve healthier ageing outcomes. This represents the largest ever public-private collaboration in The Netherlands in the area of ‘healthy ageing’.

Attenuation of the Ageing Process
Under the DuSRA-VOILA umbrella, three joined projects exist: VOILA (Vitality Oriented Innovations for the Life course of the Ageing Society), SMARTage (Senescence Models, Aging Research and Therapeutics, led by Cleara Biotech) and  Neuromet (Neuroinflammation and metabolomics). Our unique proposition is that, instead of working on a single disease condition, we want to tackle a number of conditions associated with aging. For instance, one of the teams is discovering new ‘biomarkers’ (diagnostic signal compounds), which allows assessment as to which seniors have the highest risk of accelerated ageing as well as elevated frailty during medical interventions. Another angle of research is how combinations of  life style interventions influence the health status of their metabolism, the immune system, the intestinal microbiota and the musculature.

A complementary research theme is ageing at the cellular level. In this case the research teams focus on senescent (‘rusty’) cells, their identification and their specific removal. Applying timely interventions using largely known mechanistic understanding, the researchers anticipate to attenuate disease such as heart failure, dementia and certain types of cancer.

Largest collaboration on  Healthy Ageing in The Netherlands
The VOILA consortium is a collaboration of the Medical Centers of Leiden (LUMC), Utrecht (UMC Utrecht), Groningen (notably the ERIBA Institute), Rotterdam (Erasmus MC) and Maastricht. Also Wageningen University, the Dutch Institute of Public Health (RIVM), the Leiden-Amsterdam Centre for Drug Research and the Delft University of Technology are public partners. The private partners are Royal FrieslandCampina, Cleara Biotech, Sciex, Interscience/Sample Q, &niped, Diabetes Fonds, health insurer Zorg & Zekerheid and Leyden Academy. The VOILA programme is co-financed by a grant of 6 million euros from ZonMw and Health~Holland, Topsector Life Sciences & Health. The remainder is contributed by private partners.

Read more about the programme VOILA and the Dutch Society of Research on Ageing DuSRA.

For more information or interview requests, please contact Danique van der Gaauw (ZonMw) via email / phone +31 (0)70 349 5311 or Tessa van Leeuwen (LUMC) via email / phone +31 (0)6 1137 1146.

JAMA Cardiology: focus on population level societal determinants of a healthy lifestyle

JAMA Cardiology: focus on population level societal determinants of a healthy lifestyle

In April 2019, Leyden Academy researchers Frank Schalkwijk and David van Bodegom published a Letter to the Editor in the high-impact journal JAMA Cardiology, in response to a study that showed that the gradual increase of blood pressure with age is inappropriately considered a normal characteristic of ageing. Schalkwijk and Van Bodegom argue that the finding that in Western populations the increase of blood pressure starts at early ages indicates that entire Western populations are at high risk for hypertension and cardiovascular disease. Nevertheless, in current high-risk strategies that prevail in medical practice, we wait until an individual exceeds a certain cutoff point to consider them to be at risk. This strategy has been proven effective, but for further reducing the incidence of cardiovascular disease, treating high-risk individuals even more intensively might not be the most fruitful strategy. Therefore, health care professionals should focus more on the population level societal determinants of a healthy lifestyle in addition to prevailing prevention policies that primarily rely on high-risk strategies.

Read the full article here: Absence of the Association of Blood Pressure With Age in a Remote Venezuelan Population Renews the Call for Population-Wide Interventions.

AARP special feature: Ageing in the Netherlands

AARP special feature: Ageing in the Netherlands

People across the globe share many of the same wants and needs as they grow older. This is why the AARP, America’s largest organization dedicated to empowering seniors to choose how they live as they age, also looks abroad for inspiration, innovations and insights. In the annual publication The Journal, the AARP showcases thought leadership around the globe concerning all issues related to ageing, to share promising ideas so that others might be inspired and even build off them. Each year, a specific country is explored in-depth to better understand its approach to the ageing challenge. After Japan in 2018, the AARP now decided to focus on The Netherlands, one of the small, innovative economies featured last year in the AARP’s Ageing Readiness and Competitiveness Report.

Cycling, volunteering and pickled herring
The special feature in The Journal offers a multifaceted image of ageing in the Netherlands. In a prologue, Hugo de Jonge, the Dutch Minister of Health, Welfare, and Sports, discusses how ageing in place, nursing care, and social isolation are all connected, and explains how the government aims to empower civil society, social enterprise, and companies to work together to improve care and support to seniors. Professor Joris Slaets of Leyden Academy introduces a typical Dutch older couple, Wim and Ineke, to paint a picture of what growing older in the Netherlands looks like. The Journal also includes profiles of intergenerational care community Humanitas Deventer, nursing farm De Reigershoeve, the iZi Living Lab, the Dutch cycling and volunteering culture, the age-friendly and ‘super-diverse’ city of The Hague, and many more. The Journal also introduces some older Dutch persons, like 79-year old Hans Ulrich from Oegstgeest. A picture gallery depicts ‘a day in the life’ of Hans, who represented the Leyden Academy in 2018. You can see him smoking his pipe in his garden, walking to the mall with his grandson and enjoying a pickled herring as a savory snack.

Listening to older individuals
One of the lessons Debra Whitman, Executive Vice President and Chief Public Policy Officer at the AARP, took from her visit to The Netherlands is that not all of the most forward-thinking approaches to ageing had a high-tech feel. Sometimes low-tech turns out to be exactly what the older adults in the community found most valuable. Whitman was also impressed by the prominent focus placed on human touch and caring in the Netherlands. Technology is used as an assistant to enhance the quality of life of older people, not as a substitute for human contact. “In all our work to improve the lives of older adults, we must never forget that we’re not talking about an abstract ‘population’. These are noble individuals with contributions to make and wishes to be honored. The best solutions come from listening to the people we aim to serve, and learning from them what they need, and, even more important, what they want,” she concludes. As Professor Slaets puts it in his contribution to The Journal: “From the perspective of the elderly, there is a clear demand for more individually tailored and person-centered care. Assertive baby boomers will expect and accept nothing less.”

You can find the 2019 edition of The Journal on the AARP website or download the full report here (pdf file). For a direct link to the contribution of Professor Slaets, please click here.

IMISCOE Conference ‘Care for and Social Well-being of Older Migrants’

IMISCOE Conference ‘Care for and Social Well-being of Older Migrants’

Today Leyden Academy hosted the IMISCOE conference, with the aim to bridge state-of-the-art research and practice on the care for and social well-being of older migrants.

The morning session focused on the complex interconnections of different forms of care provided by various individuals and organisations in local places (the private home, the neighbourhood, care institutions). Long-term care is increasingly decentralised to the local level, boosting new combinations of informal family care, professional care and volunteer work. On the basis of recent research from the Netherlands and Switzerland, the session explored the implications of this development for older migrants, providers of mainstream and specialised care services, and policymakers.

The afternoon session focused on different aspects of older migrants’ social well-being in the Netherlands. Although it is often referred to, the social domain of well-being remains secondary to issues of health and provision and quality of care for older migrants. This session explored which aspects of well-being are common to current research, debates and practices. and which aspects older migrants themselves acknowledge as important. The three key social themes of well-being were: loneliness, social participation and transnational living.

This conference was organised by Roos Pijpers (Radboud University Nijmegen), Eva Soom Ammann (Bern University of Applied Sciences), Tineke Fokkema (Netherlands Interdisciplinary Demographic Institute/Erasmus University Rotterdam) and Nina Conkova (Leyden Academy on Vitality and Ageing)

Technical guidance to improve the health of older refugees and migrants

Technical guidance to improve the health of older refugees and migrants

The technical guidance Health of older refugees and migrants was released in November 2018 by the WHO Regional Office for Europe. The report aims to inform policy and practice development specifically related to improving the health and wellbeing of older refugees and migrants in Europe. Ageing and migration are complex multidimensional processes, shaped by a range of factors at the micro, meso and macro levels over the life-course of the individual. Responding to the needs of older refugees and migrants, must therefore be integrated into all dimensions of ageing policies and practices across Europe. Author of this important report is Maria Kristiansen, Associate Professor at the Center for Healthy Aging and the Department of Public Health, University of Copenhagen.

Conversation tool for older migrants
The WHO technical guidance report includes several ‘promising practices’, including a project from Leyden Academy (page 21) regarding people-centered engagement of older migrants in health and long-term care. It features the Life and Vitality Assessment (LAVA), an instrument to map and discuss what older people find important in their lives. We are in the process of developing a version of the LAVA specifically for older migrants, based partly on the insights we obtained from a series of focus groups in 2018 among the largest non-Western migrant groups in the Netherlands.

For more information, please visit the WHO Regional Office for Europe website.

Whitepaper: Why do we retire?

Whitepaper: Why do we retire?

Aegon Center for Longevity and Retirement (ACLR) is publishing a series of four whitepapers to broaden the view on retirement, beyond the traditional financial scope. The series is one of the results of the long-lasting cooperation between Aegon and Leyden Academy on Vitality and Ageing. The first whitepaper was released today and examines the question: Why do we retire?

Retirement is not simply a financial issue; it is a phase of life where people aspire to stay socially connected, participate in their communities, and remain economically active. Therefore, research areas that deal with the connection between retirement and important aspects of later life such as health, vitality, life satisfaction and the image of elderly can contribute to helping people prepare for retirement and their societal position and engagement after retirement. For this reason, ACLR has invited the researchers of Leyden Academy on Vitality and Ageing to help reflect on retirement from different academic angles, and inspire Aegon to encourage the debate on retirement beyond the economic aspects.

This first whitepaper ‘Why do we retire?’ explores the various wishes and ambitions that people have for retirement, based on the combined results of the surveys of Aegon Center for Longevity and Retirement and Leyden Academy. You can read the whitepaper on the Aegon website, accompanied by a personal reflection on the issue by Mike Mansfield, Program Director at ACLR.

In the three whitepapers that follow in 2019, we will further broaden the view on retirement from the perspectives of health and vitality, well-being and life satisfaction, and finally the image of retirement and retirees.

Care for and social well-being of older migrants

Care for and social well-being of older migrants

On Tuesday 19 February 2019 the IMISCOE conference ‘Care for and social well-being of older migrants’ will be held in Leiden. In the Netherlands, the number of older adults with a migration background is growing rapidly. Due to cultural, socio-economic and demographic differences with nonmigrant older adults, older migrants generate specific care demands as well as a need for new interventions and facilities aimed at their well-being.

The conference will focus on the exchange of knowledge between researchers, professionals and policy makers in care and welfare. The researchers will present and discuss with the participants practical applications of recent research into local aspects of care for older migrants, including district-oriented work and family care, and aspects of social well-being, including loneliness, social participation and transnational relations. There will be room for supplying suggestions for follow-up research and to further strengthen the link between research and practice. For the full program and details about location please refer to the brochure.

The official language is English, and participation is free. The number of places is limited so quick registration is advised.

Aging Readiness & Competitiveness Report

Aging Readiness & Competitiveness Report

AARP released its 2018 Aging Readiness and Competitiveness (ARC) research, which examines how prepared nations are for the challenges and opportunities presented by a rapidly aging population. This year, the research examined Australia, Chile, Costa Rica, Lebanon, Mauritius, the Netherlands, New Zealand, Norway, Singapore and Taiwan.

Based on global research conducted by FP Analytics, 2018 ARC plays out against a dramatic, global demographic shift already underway.  By 2030, there will be nearly one billion people ages 65 and older around the world, a group that between 2015 and 2030 will grow at four times the rate of the overall global population.

The inaugural 2017 ARC report established a baseline understanding of the state of global aging policies, with in-depth assessments of a group of 12 countries that are geographically, culturally, and socioeconomically diverse and that, together, represent 61 percent of the global GDP and nearly half of the world’s population of people ages 65 and older. For the 2018 ARC report, the focus shifted to 10 small economies around the world that are leading their regions in responding to demographic change. As in 2017, countries were assessed on four pillars: 1. Community Social Infrastructure, 2. Productive Opportunity, 3. Technological Engagement and 4. Health Care & Wellness.

Among the notable findings in the 2018 ARC:  The World Health Organization’s Age-Friendly Cities initiative has been adopted in seven of the 10 2018 ARC nations with Taiwan most strongly embracing the model and deploying it in more than 20 of the nation’s largest cities.

While providing access to affordable, high-quality health care remains a vexing, much-debated challenge in the U.S., it is cited by the majority (54 percent) of respondents from 2018 ARC nations as the area in which their nation is strongest, with nine of 10 ARC nations (all but Lebanon) having instituted universal health care coverage.  Additionally, health care and wellness was cited by 38 percent of respondents as the category that has seen the greatest improvement in their nation over the last three to five years.
As countries increasingly digitize government services, the ARC found that the risk of digital exclusion is only growing, making targeted outreach and training for older adults vitally important.

Despite considerable satisfaction among 2018 ARC respondents with progress made in their nation around the provision of health care, dementia is nearly uniformly seen as a hurdle. With lifespans extending and the prevalence of dementia growing dramatically, all 2018 ARC countries except Lebanon and Mauritius have national plans to manage dementia.

About AARP
AARP is the nation’s largest nonprofit, nonpartisan organization dedicated to empowering people 50 and older to choose how they live as they age. With a nationwide presence and more than 38 million members, AARP strengthens communities and advocates for what matters most to families: health security, financial stability and personal fulfillment. AARP also produces the nation’s largest circulation publications: AARP The Magazine and AARP Bulletin. To learn more, visit www.aarp.org.

End-of-life care underrepresented in Dutch medical curricula

End-of-life care underrepresented in Dutch medical curricula

Leiden, The Netherlands, 25 September 2018 – Every doctor will face terminally ill patients. How can dying be properly addressed and discussed in medical practice? What does good care entail in the final phase of life? Researchers at Leyden Academy on Vitality and Ageing reviewed to what extent end-of-life care (ELC) is represented in the Dutch medical curricula. The education offered is very diverse and the subject remains underrepresented, the researchers conclude in an article published on 5 September in academic journal Perspectives on Medical Education.

Research method
Future doctors need to be trained in providing appropriate care to terminal patients. In many countries, medical curricula have been reviewed for the attention devoted to ELC. In the Netherlands, no formal review had been performed. The researchers first designed a checklist based on international standards consisting of five domains of ELC education that are considered essential, such as communication skills, juridical and ethical aspects, and self-reflection on experiences with death and loss. The checklist was used to review the Dutch Framework for Undergraduate Medical Education, which serves as a blueprint for medical education in the Netherlands. Secondly, the bachelor and master curricula and elective courses of the 8 Dutch medical faculties were studied. Is ELC being addressed, and if so how, in what educational form is it taught?

Room for improvement
The researchers conclude that there is much room for improvement. The Framework for Undergraduate Medical Education includes four of the five domains of ELC and describes the ELC-domains only superficially. None of the eight medical faculties taught all domains specifically on ELC; they were taught within other courses. Only one faculty offered an elective course that includes all essential aspects of the international standards.

ELC easily overlooked
The researchers believe that ELC is not left out of the medical curricula intentionally. Joris Slaets, Professor of Geriatric Medicine and one of the authors, explains: “Everybody agrees immediately that this is an important topic. Perhaps we all assume that end-of-life care is addressed somewhat in all courses in medical education. But this turns out not to be the case. Also, many medical specialties compete to be included in the national framework and curricula. End-of-life care is easily overlooked, since there are no real advocates pleading for its case.”

Confrontation with death
We need to better prepare young doctors for the medical practice where they will soon be confronted with death, the researchers argue. Joris Slaets: “When curative treatments are no longer effective, other skills are required of the physician: being able to have good conversations with dying patients and their families, attention to spiritual and psychosocial aspects, self-reflection. Skills that make you a better doctor, in any case. In Dutch society and politics, there is growing attention for quality of life at the end of life. It is about time that end-of-life care is adequately addressed in medical education.”

Make ELC a compulsory subject
The current Framework for Undergraduate Medical Education was introduced in 2009 and will be replaced next year. The researchers see this as a unique opportunity to firmly embed ELC in the Dutch blueprint for medical education. The medical faculties themselves can also make improvements, says Joris Slaets: “They can learn a lot from each other. Make end-of-life care a compulsory subject, address it in working groups. Providing care for a dying patient is ultimately one of the basic facets of being a doctor, regardless of which specialization you choose. Helping a person die in comfort and with dignity is truly a humbling and gratifying experience.”

The article ‘End-of-life care in the Dutch medical curricula’ by Josefien de Bruin, Mary-Joanne Verhoef, Joris P.J. Slaets and David van Bodegom was published in scientific journal Perspectives on Medical Education on 5 September 2018: https://link.springer.com/article/10.1007/s40037-018-0447-4

For more information, please contact Niels Bartels (communications manager) by phone +31 (0)71 524 0960 or by email.