Coordinator: Dr. D. van Heemst
'This course provides you with an overview of the current state of knowledge of biological mechanisms of ageing’
| ECTS Credits |
4 |
| Course level |
600 |
| Coordinator |
Dr. D. van Heemst |
| Number of classes (1.5 hrs) |
12 |
| Period |
24 September 2012- 21 October 2012 |
| Lectures |
Monday and Tuesday 09:00-13:00 |
| Examination |
Grant proposal |
| Admission |
Open; completed bachelor degree |
| Costs |
600 euro (with ECTS)
300 euro (with certificate)
Registered students at Leiden University: no fee
Register here |
This course will focus on why and how we age. Students will not only obtain a thorough understanding of biological mechanisms of ageing and development, but will also learn various fundamental evolutionary theories of ageing and will be able translate these theories into genetic mechanisms and the type of genes that underlie them. In addition, the students will become familiar with the ‘free radical theory of ageing’, the anti-oxidant protection mechanism and repair processes that play a role in the defense against free radical damage will be discussed. During the course, numerous scientific articles will be read and discussed; a visit to a laboratory is part of the course work.
Themes
Neuro-endocrine regulation of longevity
Evolutionarily conserved pathways
Model organisms
Growth and development & ageing
Energy metabolism
Protein aggregation
Proteotoxicity
Lecturers
There will be a wide variety of lecturers. The lecturers for 2012-2013 are not yet confirmed, to provide an idea, the 2011-2012 lecturers were:
Drs. A. Akintola
Department of Gerontology and Geriatrics, Leiden University Medical Center
Dr. E.A.A. Bollen
Department of Genetics, University Medical Center Groningen
S. Bulterijs
University of Ghent
Dr. A.D.N.J. de Grey
SENS Foundation, El Granada
Prof. dr. J.H. Hoeijmakers
Department of Genetics, Erasmus Medical Center
Dr. W.D. van Marken Lichtenbelt
Department of Human Biology, Maastricht University Medical Center
Prof. dr. J.H. Meijer
Department of Neurophysiology, Leiden University Medical Center
Prof. dr. H. Pijl
Department of Endocrinology and Metabolism, Leiden University Medical Center
Drs. B. Sabayan
Department of Gerontology and Geriatrics, Leiden University Medical Center, the
Prof. dr. M. Tatar
Division of Biology and Medicine, Brown University, Providence,
Prof. dr. R.G.J. Westendorp
Leiden University Medical Center, the Netherlands
Leyden Academy on Vitality and Ageing